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. 2023 Mar 2;23:199. doi: 10.1186/s12885-023-10675-y

Fig. 3.

Fig. 3

Identification of master regulatory networks across macrophage subsets. a Heatmap showing the normalized activity score of representative regulons across different macrophage subsets. b t-SNE plots based on activity score of 94 regulons and colored by annotations inferred from whole transcriptome profiling. c t-SNE plots showing activities of IRF1, STAT3, EZH2, KLF5, TCF4, and HES4 regulons. *g included in the parenthesis represents the number of genes in the regulons. PC, principal component; AUC, the area under the curve