Table 1.

Model parameters and their biological interpretation.

Parameter	Biological meaning
ρ	Proliferation rate of glioma cells
K	Carrying capacity of glioma cells
p	Rate of CAR T-cell expansion induced by glioma
θ	Death rate of CAR T-cells
g	Steepness coefficient of CAR T-cell expansion
$k_1^{(n)}$	Binding rate of CAR T-cell and conjugate In−1
$k_{-1}^{(n)}$	Detaching rate of CAR T-cell and conjugate In
$k_{n+2}^{(n)}$	Death rate of glioma cells from conjugate In
${k_i^{(n)}|}_{i=2}^{n+1}$	Death rate of CAR T-cells from conjugate In