Table 1.
Model parameters and their biological interpretation.
Parameter | Biological meaning |
---|---|
ρ | Proliferation rate of glioma cells |
K | Carrying capacity of glioma cells |
p | Rate of CAR T-cell expansion induced by glioma |
θ | Death rate of CAR T-cells |
g | Steepness coefficient of CAR T-cell expansion |
Binding rate of CAR T-cell and conjugate In−1 | |
Detaching rate of CAR T-cell and conjugate In | |
Death rate of glioma cells from conjugate In | |
Death rate of CAR T-cells from conjugate In |