Figure 13.

Histologic analysis of retina at posterior pole. Transverse sections of flat-mounted retina embedded in JB-4 were stained with PAS and hematoxylin (H). At low magnification, a clear subretinal structure (between arrows) can be observed in the atrophic area where the outer nuclear layer is absent (A). Higher magnification of area “b” demonstrates a thick fibrous structure (bracket) below a thick basal laminar deposit (paired arrow) (B). This fibrous membrane represents the subretinal glial membrane observed in the flat perspective (Figures 10–12). Subducted RPEs in area “c” of panel A are observed between two membranes (C). In area “d” of panel A, neovascularization is observed with capillaries (arrows) below subducted RPE (paired arrows). Scale bars: 200 µm (A) and 20 µm (B, C).