Table 1.
Aged Control and GA Donor Eyes Used in This Study
| Donor | Age at Death, y | COD | DET/PMT | Ethnicity/Sex | Eye | Postmortem Gross Observation |
|---|---|---|---|---|---|---|
| AC1 | 84 | MI | 9.0/27.8 | C/M | OS | Unremarkable |
| AC2 | 75 | UTI | 5.0/30.0 | C/F | OD | Unremarkable |
| AC3 | 76 | CA | 5.0/22.0 | C/F | OS | Unremarkable |
| AC4 | 71 | CA | 4.9/24.5 | C/M | OS | Unremarkable |
| AC5 | 100 | CA | 5.6/27.5 | C/F | OD | Unremarkable |
| GA1 | 90 | CA | 5.8/32.0 | C/M | OD | RPE atrophy in macula |
| GA2 | 92 | CA | ?/27 | C/M | OD | RPE atrophy in posterior pole and peripapillary region, scattered drusen outside atrophic area |
| GA3 | 98 | CAN | 14.0/48.0 | C/M | OS | RPE atrophy in posterior pole and peripapillary region, scattered drusen outside atrophic area |
Postmortem definitions: Unremarkable = no signs of pathology in retina, RPE, or choroid; no drusen present. AC, aged control; C, Caucasian; CA, cardiac arrest; CAN, cancer; COD, cause of death; DET, death to enucleation; MI, myocardial infarct; PMT, post mortem time; UTI, urinary tract infection.