Figure 2. Effects of the in vitro digestion on MgO.

(A and A’) Transmission electron microscopy (TEM) images of stomach digested MgO (yellow arrows indicates a lattice fringe effect from MgO-NPs embedded in organic material). (C and C’) TEM images of fully digested MgO (yellow arrows indicates a lattice fringe effect from MgO-NPs embedded in inorganic material). (B and D) EDS spectra showing the presence of magnesium (Mg) and oxygen (O) in stomach and fully digested samples, respectively. (E and F) Hydrodynamic size (nm) distribution of digested MgO in stomach and intestine, respectively, measured by NTA. (G) Net content of ionic magnesium (Mg+) detected in the supernatant of food additive MgO samples analyzed by inductive coupled plasma – mass spectrometry. Data shown as mean±SEM.