Fig 4. Combined decitabine and Taxol decreases MCF-7/Taxol cells proliferation and can improve their chemosensitivity.
A. Cell growth inhibition rate of breast cancer cell lines was determined by CCK-8 assay after demethylation with 0.5uM decitabine and treatment with different concentrations of Taxol for 24h. B. Cell growth inhibition rate was showed by CCK-8 assay after demethylation with 0.5 uM decitabine and treatment with 640 nM Taxol. C. Cell proliferation was determined after treatment with different concentrations of Taxol for 72h. Data are expressed as the mean ± SD of three independent experiments. ***P<0.001 vs control group, ###P<0.001 vs control group.