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. 2023 Mar 3;9(9):eabo4616. doi: 10.1126/sciadv.abo4616

Fig. 4. Cardiac function was improved after echo-guided sEV administration to ischemic heart.

Fig. 4.

(A) Representative images of in vivo live imaging of sEVs after echo-guided intramyocardial injection into ischemic heart. Fluorescent images of rats shown 7 days after echo-guided myocardial injection of sEVs (5 μg/kg). (B) Quantification of average radiant efficiency [(p/s/cm2)/(sr/μW/cm2)] from the rat heart. (C) Left ventricular EF and (D) left ventricular FS measured at day 28 after sEV injection. *P < 0.05 and **P < 0.01.