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. 2023 Feb 10;12:e84245. doi: 10.7554/eLife.84245

Table 3. Characteristics of FY2021 and FY2010 RPGs according to solicitation status.

Characteristic Solicited 2021 Unsolicited 2021 Solicited 2010 Unsolicited 2010
Total N (%) 16042 (40.6) 23471 (59.4) 9697 (28.0) 24986 (72.0)
Total Costs ($M BRDPI) Mean (SD) 0.71 (1.36) 0.48 (0.31) 0.65 (1.28) 0.52 (0.47)
Log-10 Total Costs BRDPI Mean (SD) 5.69 (0.33) 5.63 (0.20) 5.65 (0.35) 5.66 (0.20)
R01-Equivalent Yes 10621 (66.2) 20637 (87.9) 6677 (68.9) 22196 (88.8)
R21 or R03 Yes 2750 (17.1) 2199 (9.4) 2248 (23.2) 1857 (7.4)
Costs > $5 million BRDPI Yes 121 (0.8) 14 (0.1) 55 (0.6) 32 (0.1)
Cooperative Agreement Yes 2327 (14.5) 77 (0.3) 1478 (15.2) 208 (0.8)
Clinical Trial Yes 3104 (19.3) 1072 (4.6) 1335 (13.8) 1067 (4.3)
Human or Animal Neither 3407 (21.2) 4220 (18.0) 1632 (16.8) 5096 (20.4)
Animal 4579 (28.5) 12054 (51.4) 3151 (32.5) 12696 (50.8)
Human 6823 (42.5) 4997 (21.3) 4287 (44.2) 5347 (21.4)
Both 1233 (7.7) 2200 (9.4) 627 (6.5) 1847 (7.4)
Organization Type Institute of Higher Education 12983 (80.9) 19581 (83.4) 7662 (79.0) 20848 (83.4)
Research Organization 1214 (7.6) 1384 (5.9) 902 (9.3) 1836 (7.3)
Independent Hospital 1419 (8.8) 2076 (8.8) 824 (8.5) 1824 (7.3)
Other 426 (2.7) 430 (1.8) 309 (3.2) 478 (1.9)

RPG = Research Project Grant. BRDPI = Biomedical Research and Development Price Index. All BRDPI-adjusted costs are based on an FY2021 reference (in other words, basedon 2021 dollars).