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. 2023 Feb 10;12:e84245. doi: 10.7554/eLife.84245

Table 4. Characteristics of FY2021 and FY2010 R01 equivalent grant awards according to solicitation status.

Characteristic Solicited 2021 Unsolicited 2021 Solicited 2010 Unsolicited 2010
Total N (%) 10621 (34.0) 20637 (66.0) 6677 (23.1) 22,196 (76.9)
Total Costs ($M BRDPI) Mean (SD) 0.67 (0.73) 0.51 (0.30) 0.74 (1.19) 0.50 (0.38)
Log-10 Total Costs BRDPI Mean (SD) 5.74 (0.24) 5.67 (0.15) 5.75 (0.27) 5.67 (0.15)
Nominal Direct Costs ($M) Mean (SD) 0.47 (0.62) 0.34 (0.23) 0.42 (0.78) 0.27 (0.26)
Nominal Direct Costs $250 K or Less Yes 3049 (28.7) 7302 (35.4) 3121 (46.7) 15,702 (70.7)
Nominal Direct Costs $500 K or More Yes 2460 (23.2) 1990 (9.6) 1191 (17.8) 832 (3.7)
Costs > $5 million BRDPI Yes 35 (0.3) 12 (0.1) 44 (0.7) 26 (0.1)
Clinical Trial Yes 2126 (20.0) 920 (4.5) 976 (14.6) 927 (4.2)
Human or Animal Neither 2337 (22.0) 3436 (16.6) 1017 (15.2) 4525 (20.4)
Animal 2902 (27.3) 10719 (51.9) 2202 (33.0) 11,451 (51.6)
Human 4656 (43.8) 4367 (21.2) 3055 (45.8) 4686 (21.1)
Both 726 (6.8) 2115 (10.2) 403 (6.0) 1534 (6.9)
Organization Type Institute of Higher Education 8650 (81.4) 17161 (83.2) 5259 (78.8) 18,519 (83.4)
Research Organization 791 (7.4) 1216 (5.9) 632 (9.5) 1639 (7.4)
Independent Hospital 904 (8.5) 1880 (9.1) 579 (8.7) 1604 (7.2)
Other 276 (2.6) 380 (1.8) 207 (3.1) 434 (2.0)

BRDPI = BiomedicalResearch and Development Price Index. All BRDPI-adjusted costs are based on an FY2021 reference (in other words, based on 2021dollars).