Figure 4. Single-chromosome distance dictates nRNA correlation.
(A) The correlation coefficients between genes as a function of single-chromosome distance. (B) Average correlation coefficients of genes given that their genomic distance and single-chromosomal distance were within a specific range. An * illustrates whether the average correlation coefficients along that dimension are correlated (p-value<0.01) (Appendix 1). (C) The mean-squared displacement of active TFF1, the fitted line, and 95% CI shaded (error bars are individual 95% CIs). (D) The average number of chromosomes with nRNA for gene given the distance between gene and divided by the average with all distances. (E) The optimal function for the model that results in the black curve in (F). (F) The correlation–distance relationship for all pairs of genes from the simulation utilizing the function in (E). The boxplots here are from simulation, red curve is shown for reference and is the experimental data from (A). (G) The same as (F) but on a different scale. (H) The results of the simulation without resolution error of the experiment. (I) Simulation results without resolution error and with nRNAs having a deterministic on time. (J) Simulation results without resolution error, with deterministic on times, and no chromatin diffusion for all pairs of genes.