Figure 4. Single-chromosome distance dictates nRNA correlation.

(A) The correlation coefficients between genes as a function of single-chromosome distance. (B) Average correlation coefficients of genes given that their genomic distance and single-chromosomal distance were within a specific range. An * illustrates whether the average correlation coefficients along that dimension are correlated (p-value<0.01) (Appendix 1). (C) The mean-squared displacement of active TFF1, the fitted line, and 95% CI shaded (error bars are individual 95% CIs). (D) The average number of chromosomes with nRNA for gene $i$ given the distance between gene $j$ and $i$ divided by the average with all distances. (E) The optimal $\omega$ function for the model that results in the black curve in (F). (F) The correlation–distance relationship for all pairs of genes from the simulation utilizing the $\omega$ function in (E). The boxplots here are from simulation, red curve is shown for reference and is the experimental data from (A). (G) The same as (F) but on a different scale. (H) The results of the simulation without resolution error of the experiment. (I) Simulation results without resolution error and with nRNAs having a deterministic on time. (J) Simulation results without resolution error, with deterministic on times, and no chromatin diffusion for all pairs of genes.