Figure 7. The phenotypes of neurons made by thoracic neuroblast (NB) 4–2 during its embryonic and postembryonic phases of neurogenesis.
Neurons are generated pairwise during both phases to produce the 13A and 13B hemilineages. (A) Four examples of embryonic born, 13B interneurons that function in the larva. All are commissural interneurons having ipsilateral dendrites and contralateral output sites. Boxed image shows the neurons overlapping in segment T1. (B) Example of a postembryonic clone of NB4-2 showing the neurons of the two hemilineages at the end of larval life. (C) Confocal projection of the adult form of larval-born, 13B interneurons expressed in the SS04739 driver line. (D, E) The larval and adult phenotypes of one of the embryonic born 13B interneurons, T13t. (D) shows the three pairs of T13t neurons as revealed by the SS02006 driver line. (E) shows Flip-switch clones of the same cells showing their adult phenotypes.
Figure 7—figure supplement 1. Confocal images of dorsal (top) and transverse (bottom) views of the early metamorphosis of the T3 pair of T13t cells: the dendritic arbor is gone by 8 hr after pupariation (P+8h), contralateral growth cones are evident by P+24h, and the arbor is near its maximal extent by P+48h.
