Figure 3. Association of Percentage Increase in Concentration of Total Tau (T‐Tau), Neurofilament Light Chain (NfL), and Glial Fibrillary Acidic Protein (GFAP) With Change in Standardized Units of Global Cognition, Episodic Memory, and Executive Functioning in a Biracial Population Sample.

Percent change in the neurological biomarkers for change in SD unit for global cognition (A), episodic memory (B) and executive function (C). The relationship of change in serum concentrations of total tau, neurofilament light chain, and glial fibrillary acidic protein with cognitive function was adjusted for age, female sex, Black race, education, and the ApoE4 allele.