Table 2.
DSM-5 diagnosis | Gene-absent n = 25 |
Gene-present n = 24 |
---|---|---|
Major depressive disorder1 | ||
Current (%) Remission (%) Lifetime (%) No. of episodes, mean (SD) Age of onset, mean (SD) |
9 (36) 3 (12) 20 (80) 2.86 (2.96) 16.24 (4.41) |
8 (33) 2 (8) 20 (87) 5.32 (8.35) 15.65 (3.50) |
Anxiety disorder (%) Age of onset, mean (SD) |
9 (36) 13.00 (3.63) |
8 (33) 15.86 (8.71) |
Substance/alcohol use disorder (%) Severity, mean (SD) (/4) Age of onset, mean (SD) |
7 (28) 2.08 (0.80) 18.50 (0.58) |
6 (25) 2.17 (0.98) 18.40 (1.82) |
Eating disorder (%) Severity, mean (SD) (/4) |
2 (8) 1.67 (2.08) |
2 (8) 2.50 (1.73) |
These data were ascertained by a clinical interview using the Mini-International Neuropsychiatric Interview DSM-5 (MINI-5). 1Percentages do not add up to 100, because some participants with a current major depressive episode also had a past episode (i.e., current and lifetime). No participants in either condition met criteria for bipolar disorder, mania, or psychosis, as per exclusion criteria. Severity scores were calculated on a 4-point Likert-type scale. Anxiety disorder = panic disorder, agoraphobia, social anxiety disorder, obsessive compulsive disorder, generalized anxiety disorder. Eating disorder = bulimia, binge eating.