Table 3.

Multivariate analysis of predictive factors for lactate level in sepsis patients.

	B value	95% CI of B value		T	P value
		Lower limit	Upper limit
(Constant)	5.262	3.244	7.280	5.118	<0.001
APACHE II score	0.066	0.030	0.102	3.607	<0.001
SOFA score	0.026	−0.048	0.100	0.689	0.491
PLT	0.001	−0.001	0.003	0.697	0.486
PT	−0.001	−0.009	0.008	−0.174	0.862
APTT	0.016	0.006	0.026	3.058	0.002
TBIL	0.005	0.001	0.009	2.517	0.012
LDH	0.000	0.000	0.000	5.599	<0.001
eGFR	−0.005	−0.011	0.002	−1.493	0.136
CRE	−0.002	−0.003	0.000	−2.088	0.037
Refractory hypotension	−0.819	−1.238	−0.400	−3.837	<0.001
Use of vasoactive drugs	−0.273	−0.892	0.346	−0.865	0.387
Use of glucocorticoid	−0.391	−0.805	0.023	−1.855	0.064
Mechanical ventilation	0.095	−0.441	0.631	0.348	0.728
CRRT	−1.356	−1.826	−0.886	−5.660	<0.001
Chronic liver disease	0.736	−0.110	1.582	1.707	0.088
Chronic kidney disease	−0.923	−1.653	−0.194	−2.484	0.013
Autoimmune disease	0.311	−0.428	1.049	0.826	0.409
Malignancy	0.174	−0.319	0.668	0.694	0.488

APACHE II, acute physiology and chronic health evaluation II; SOFA, sepsis-related organ failure assessment; PLT, platelet count; PT, prothrombin time; APTT, activated partial thromboplastin time; TBIL, total bilirubin; LDH, lactate dehydrogenase; CRE, creatinine; eGFR, estimated glomerular filtration rate; CRRT, continuous renal replacement therapy. In the multiple linear regression model, adjusted R² = 0.232, F = 14.940, P < 0.001.