Table 4.
Baseline data and fluid resuscitation comparison of patients in the high lactate group and the low lactate group.
| Characteristic | Low lactate (n = 394) | High lactate (n = 436) | P value |
|---|---|---|---|
| Baseline date | |||
| Male (%) | 244 (61.9) | 277 (63.5) | 0.633b |
| Age (years) | 63 (52–73) | 63 (51–73) | 0.719a |
| Weight (kg) | 65 (55–70) | 65 (55–70) | 0.875a |
| Hospital stay (days) | 18 (11–30) | 15 (8–27) | <0.001a |
| ICU stay (days) | 8 (4–15) | 7 (3–14) | 0.018a |
| Drinking history, yes (%) | 45 (11.4) | 51 (11.7) | 0.901b |
| Smoking history, yes (%) | 51 (12.9) | 55 (12.6) | 0.887b |
| Underlying disease, yes (%) | |||
| Hypertension | 154 (39.1) | 152 (34.9) | 0.208b |
| Diabetes | 84 (21.3) | 95 (21.8) | 0.870b |
| Chronic liver disease | 16 (4.1) | 31 (7.1) | 0.058b |
| Chronic kidney disease | 44 (11.2) | 35 (8) | 0.124b |
| Chronic respiratory disease | 28 (7.1) | 30 (6.9) | 0.899b |
| Cardiovascular disease | 78 (19.8) | 83 (19) | 0.782b |
| Autoimmune disease | 27 (6.9) | 37 (8.5) | 0.378b |
| Malignancy | 64 (16.2) | 89 (20.4) | 0.122b |
| Cerebrovascular disease | 74 (18.8) | 63 (14.4) | 0.136b |
| Types of underlying disease ≥ 2 | 171 (43.4) | 170 (39) | 0.197b |
| Fluid resuscitation | |||
| Fluid resuscitation volume (3H) (mL) | 250 (150–525) | 398 (200–720) | <0.001a |
| Fluid resuscitation volume (6H) (mL) | 714.5 (495.8–1106) | 967 (621.5–1480) | <0.001a |
| Fluid resuscitation volume (12H) (mL) | 1627 (1160–2120) | 1966 (1372.5–2673) | <0.001a |
| Fluid resuscitation volume (24H) (mL) | 3249 (2530–4074) | 3701 (2949–4937.5) | <0.001a |
| Fluid resuscitation volume (3H) ≥ 30 mL/kg (%) | 4 (1.0) | 7 (1.6) | 0.458b |
| Fluid resuscitation volume (6H) ≥ 30 mL/kg (%) | 39 (9.9) | 64 (14.7) | 0.037b |
| Fluid resuscitation volume (12H) ≥ 30 mL/kg (%) | 141 (35.8) | 231 (53.0) | <0.001b |
| Fluid resuscitation volume (24H) ≥ 30 mL/kg (%) | 350 (88.8) | 415 (95.2) | 0.001b |
aNonparametric test: Mann-WhitneyU test. And the corresponding data were expressed as median (interquartile range). bChi-square tests and the corresponding data were expressed as numbers (percentages). 3H, 6H, 12H, and 24H, mean the first 3 hours, 6 hours, 12 hours, and 24 hours after ICU admission.