Table 5.
Organ dysfunction and clinical outcome comparison of patients in the high lactate group and the low lactate group.
| Low lactate n = 394 | High lactate n = 436 | P value | |
|---|---|---|---|
| Hospital stay (days) | 18 (11–30) | 15 (8–27) | <0.001a |
| ICU stay (days) | 8 (4–15) | 7 (3–14) | 0.018a |
| Hospital mortality (%) | 150 (38.1) | 268 (61.5) | <0.001b |
| APACHE II score | 18 (13–23) | 22 (18–26) | <0.001a |
| SOFA score | 8 (5–11) | 10 (8–13) | <0.001a |
| PT (S) | 15.6 (14.4–17.3) | 17.4 (15.6–20.4) | <0.001a |
| APTT (S) | 42.2 (37.0–49.5) | 45.3 (38.8–54.4) | <0.001a |
| TBIL (μmol/L) | 16.95 (10.80–30.64) | 23 (13.25–40.97) | <0.001a |
| CRE (μmol/L) | 100.2 (61.6–205.5) | 126.6 (79.15–244.75) | 0.001a |
| Refractory hypotension | 139 (35.3) | 233 (53.4) | <0.001b |
| CRRT | 90 (22.8) | 166 (38.1) | <0.001b |
aNonparametric test: Mann-WhitneyU test. And the corresponding data were expressed as median (interquartile range). bChi-square tests and the corresponding data were expressed as numbers (percentages). APACHE II, acute physiology and chronic health evaluation II; SOFA, sepsis-related organ failure assessment; PT, prothrombin time; APTT, activated partial thromboplastin time; TBIL, total bilirubin; CRE, creatinine; CRRT, continuous renal replacement therapy.