Table 6.
Multivariate analysis of predictive factors for hospital mortality of patients in the low lactate group.
| Variables | OR (95% CI) | P value |
|---|---|---|
| Age | 0.966 (0.945–0.987) | 0.002 |
| ICU stay | 1.006 (0.985–1.028) | 0.575 |
| Chronic kidney disease | 0.498 (0.174–1.427) | 0.194 |
| Cardiovascular disease | 0.930 (0.406–2.127) | 0.863 |
| Malignancy | 0.148 (0.061–0.359) | <0.001 |
| Cerebrovascular disease | 0.600 (0.256–1.407) | 0.240 |
| Types of underlying disease ≥ 2 | 0.932 (0.417–2.086) | 0.864 |
| Use of vasoactive drugs | 4.745 (1.876–11.999) | 0.001 |
| Use of glucocorticoid | 2.579 (1.321–5.034) | 0.005 |
| Mechanical ventilation | 2.926 (1.151–7.442) | 0.024 |
| CRRT | 3.079 (1.435–6.607) | 0.004 |
| APACHE II score | 0.964 (0.904–1.027) | 0.257 |
| SOFA score | 1.084 (0.963–1.220) | 0.183 |
| GCS score | 1.065 (0.978–1.159) | 0.148 |
| Hb | 1.006 (0.993–1.018) | 0.385 |
| RDW | 0.956 (0.888–1.030) | 0.235 |
| TBIL | 0.996 (0.988–1.005) | 0.436 |
| ALT | 1.001 (1.000–1.002) | 0.060 |
| LDH | 0.999 (0.999–0.9998) | 0.006 |
| Serum potassium | 0.885 (0.601–1.303) | 0.537 |
| Serum sodium | 0.982 (0.943–1.022) | 0.364 |
| HCO3 | 0.996 (0.944–1.051) | 0.893 |
| PCT | 1.003 (0.995–1.011) | 0.454 |
| Fluid resuscitation volume (3H) | 1.000 (0.999–1.002) | 0.748 |
| Fluid resuscitation volume (6H) | 0.999 (0.997–1.000) | 0.151 |
| Fluid resuscitation volume (12H) | 1.000 (0.999–1.001) | 0.648 |
| Fluid resuscitation volume (24H) | 1.000 (1.000–1.001) | 0.067 |
| Albumin infusion volume (12H) | 0.977 (0.946–1.009) | 0.157 |
| Albumin infusion volume (24H) | 1.021 (0.998–1.045) | 0.078 |
| Fluid resuscitation volume (6H) ≥30 mL/kg | 22.621 (2.987–171.333) | 0.003 |
| Fluid resuscitation volume (12H) ≥30 mL/kg | 0.600 (0.247–1.457) | 0.260 |
Note. The univariate significant indicators in Supplementary Table 2 were included in the multivariate logistic regression analysis. CRRT, continuous renal replacement therapy; APACHE II, acute physiology and chronic health evaluation II; SOFA, sepsis-related organ failure assessment; GCS, Glasgow coma scale; Hb, hemoglobin; RDW, red blood cell distribution width; TBIL, total bilirubin; ALT, alanine aminotransferase; LDH, lactate dehydrogenase; HCO3, serum bicarbonate concentration; PCT, procalcitonin.