Figure 1.
Time-activity curves (TACs) of the mouse myocardium upon tail-vein injections of 18F-flurpiridaz. (A). Native TACs after rest (18F-flurpiridaz) and stress (18F-flurpiridaz + regadenoson) injection, presented as kBq per voxel. The model curve was fitted with a single exponential model to subtract 18F-flurpiridaz injection 1 from injection 2. (B) Final rest and stress TACs after correction for injected 18F-flurpiridaz dose, presented as percent injected dose per gram tissue (%ID/g). Note that the correction of the stress curve was performed prior to the normalization to the injected dose