Table 1.
Demographic and clinical data of study patients with post-partum depression (PPD).
| Mean age (years) | 31 (24–41) N = 18 (%) |
||
| Race/ethnicity | |||
| Non-Hispanic white | 16 (88) | ||
| Hispanic white | 1 (6) | ||
| Other, Non-Hispanic | 1 (6) | ||
| Marital status | |||
| Married | 16 (88) | ||
| Domestic partner | 1 (6) | ||
| Legally separated | 1 (6) | ||
| Patient characteristics | Statistic N = 18 (%) |
HAM-D score baseline (SD) | HAM-D score post infusion (SD) |
| Presence of psychiatric comorbidity/historya | |||
| No | 0 | – | – |
| Yes | 18 (100) | 23 (5) | 11 (7) |
| Concurrent psychiatric treatment | |||
| None | 1 (6) | 23 (0) | 12 (0) |
| Single psychotropic | 4 (22) | 25 (3) | 8 (3) |
| Two psychotropics | 4 (22) | 22 (3) | 12 (7) |
| Three psychotropics | 5 (28) | 22 (7) | 10 (8) |
| Four psychotropics | 4 (22) | 25 (4) | 15 (7) |
| Psychotropic class typeb | |||
| SSRI | 12 (67) | ||
| SGA | 9 (50) | ||
| Mood stabilizer | 5 (28) | ||
| Benzodiazepine | 3 (17) | ||
| Anxiolytic | 3 (17) | ||
| SNRI | 2 (11) | ||
| SARI | 2 (11) | ||
| NDRI | 2 (11) | ||
| Antihistamine | 2 (11) | ||
| Beta blocker | 1 (6) | ||
| Alpha blocker | 1 (6) | ||
| Anti-epileptic | 1 (6) |
SD: standard deviation.
Psychiatric Comorbidity/History includes: anxiety (67%), previous PPD episodes (39%), past major depressive episodes (33%), and PTSD (22%).
SSRI (selective serotonin reuptake inhibitor): sertraline, escitalopram, fluoxetine. SGA (second generation antipsychotic): quetiapine, aripiprazole, lurasidone, olanzapine. Mood stabilizer: lithium. Benzodiazepines: clonazepam, ativan. Anxiolytic: buspar. SNRI (serotonin norepinephrine reuptake inhibitor): desvenlafaxine, duloxetine. SARI (serotonin 2 antagonist/reuptake inhibitor): trazodone. NDRI (norepinephrine dopamine reuptake inhibitor): Wellbutrin. Antihistamine: vistaril, Benadryl. Beta blocker: propranolol. Alpha blocker: prazosin. Anti-epileptic: pregabalin.