Table 3.
Weight and body mass index (BMI) change in response to liraglutide treatment
| Characteristic, average | Patients (n=68) | p-value |
|---|---|---|
| Average BMI (kg/m2) | ||
| Prior to bariatric surgery | 44.8 (37.1–50.5) | p < 0.001 |
| At weight nadir | 34.6 (30.8–37.3) | |
| Prior to liraglutide start | 35.2 (31.6–41.3) | p < 0.001 |
| After liraglutide | 32.3 (29.8–39.6) | |
| Change | 1.85 (0.85–3.25) | p < 0.001 |
| Average weight (kg) | ||
| Prior to bariatric surgery | 117.4 (100.6–142.6) | p < 0.001 |
| At weight nadir | 89.1 (82.5–105.7) | |
| Prior to liraglutide start | 95.8 (93.4–117.6) | p < 0.001 |
| After liraglutide | 90.3 (78.5–113.1) | |
| Change | 5.2 ( 2.2–6.6) | p < 0.001 |
| Patients who lost weight on liraglutide | 61 (89.7%) | |
| Patients who responded well to liraglutide (>10% EBWL) | 15 (22.1%) | |
| % total body weight loss on liraglutide | 5.30% (2.23–8.35%) | |
| % total body weight loss by bariatric surgery | p < 0.031 | |
| Laparoscopic sleeve gastrectomy | 3.63% (2.02–6.11) | |
| Laparoscopic gastric band | 4.76% (0.84–9.22) | |
| Roux-en-Y gastric bypass | 6.39% (5.30–13.0) | |
| Other | 5.76% (1.91–5.89) | |