Table 2.
Comparison of characteristics of patients with gestational diabetes mellitus (GDM) and unaffected, age-matched women as controls (CTRL)
| GDM | CTRL | p-value | |
|---|---|---|---|
| n = 159 | n = 318 | ||
| Index pregnancy | |||
| Maternal age, y | 29.8 ± 4.6 | 29.8 ± 4.6 | 0.944 |
| Pregravid BMI, kg/m2 | 28.3 (23.9–34.7) | 23.2 (20.8–25.9) | < 0.001 |
| Gravidity, n | 2 (1–3) | 2 (1–3) | 0.536 |
| Parity, n | 1 (1–2) | 1 (1–2) | 0.508 |
| Gestational age at delivery, weeks | 39 (38–40) | 39 (38–40) | 0.183 |
| Umbilical artery pH | 7.27 ± 0.073 | 7.28 ± 0.074 | 0.040 |
| APGAR 5 min | 10 (9–10) | 10 (9–10) | 0.085 |
| Birth weight, g | 3521 ± 479 | 3399 ± 525 | 0.014 |
| Birth weight centile | 56 (32–79) | 48 (25–74) | 0.007 |
| NICU, n (%) | 17 (10.7%) | 16 (5.0) | 0.034 |
| Weight gain during pregnancy, kg | 12 (8–17) | 14 (11–19) | < 0.001 |
| Excessive weight gain, n (%) | 76 (48.4) | 144 (45.3) | 0.625 |
| Caesarean section, n (%) | 46 (28.9) | 66 (20.8) | 0.052 |
| GDM w/o recurrence | CTRL | p-value | |
|---|---|---|---|
| n = 44 | n = 318 | ||
| Subsequent pregnancy | |||
| Maternal age, y | 32.9 ± 4.9 | 32.4 ± 4.6 | 0.499 |
| Pregravid BMI (kg/m2) | 26.6 (22.0–34.4) | 23.7 (21.3–27.6) | 0.006 |
| Weight gain during pregnancy, kg | 12.5 (8–16.8) | 13.5 (10–18) | 0.127 |
| Interpregnancy weight gain, kg | 1 (− 3 to 7) | 2 (− 1 to 6) | 0.555 |
| Time between pregnancies, months | 21.5 (11.3–27.8) | 21 (12–30) | 0.605 |
| Gestational age at delivery, weeks | 39 (38–40) | 39 (38–40) | 0.967 |
| Umbilical artery (pH) | 7.28 ± 0.078 | 7.29 ± 0.076 | 0.996 |
| APGAR 5 min | 10 (9–10) | 10 (9–10) | 0.299 |
| Birth weight, g | 3543 ± 680 | 3499 ± 608 | 0.659 |
| Birth weight centile | 67.5 (35–83.3) | 58 (33.8–79.3) | 0.550 |
| NICU, n | 2 (4.5) | 19 (6.0) | 0.761 |
| Excessive weight gain, n (%) | 18 (40.9) | 141 (44.3) | 0.747 |
| Caesarean section, n (%) | 10 (22.7%) | 62 (19.5%) | 0.687 |
Data are presented as mean ± standard deviation, median with interquartile range or with absolute and relative frequencies