Figure 3.

Photoinduced Ca²⁺ transients in Ziapin2-loaded hiPSC-CMs

(A) Representative Ca²⁺ transients (CaTs) recorded on the same Ziapin2-loaded cell first in dark condition (dark, in black) and subsequently photostimulated with a 200 ms pulse (l.s., in teal) at light power density = 273 μW/mm².

(B) Frequency of CaTs, (C) CaT amplitude (CaT Amp), (D) CaT rise-time (t_peak), (E) Diastolic Ca²⁺ (CaD), and (F) CaT decay kinetics (τ_decay). The paired measurements were carried out at room temperature (24°C) on 63 cells. Data are represented as mean ± SEM. ∗∗∗∗p < 0.0001.