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. 2022 Feb 17;19(1):155–162. doi: 10.1007/s11302-022-09848-4

Table 2.

Genotypic and allelic distribution of the P2Y12R gene between all patients and controls

SNP Genetic model Genotype/allele Cases Controls OR 95% CI p value
rs1491974 Codominant AA vs. AG vs. GG 27 (15.3%)/88 (50.0%)/61 (34.7%) 14 (28.0%)/26 (52.0%)/10 (20.0%) - - 0.047*
Allele contrast A vs. G 142 (40.3%)/210 (59.7%) 54 (54.0%)/46 (46.0%) 0.576 0.368–0.901 0.015*
Dominant GG vs. AG+AA 61 (34.7%)/115 (65.3%) 10 (20.0%)/40 (80.0%) 2.122 0.993–4.534 0.049*
Recessive AG+GG vs. AA 149 (84.7%)/27 (15.3%) 36 (72.0%)/14 (28.0%) 2.146 1.023–4.503 0.040*
Overdominant AA+GG vs. AG 88 (50.0%)/88 (50.0%) 24 (48.0%)/26 (52.0%) 1.083 0.578–2.031 0.803
rs6798347 Codominant AA vs. AG vs. GG 7 (4.0%)/61 (34.6%)/108 (61.4%) 6 (12.0%)/19 (38.0%)/25 (50.0%) - - 0.069
Allele contrast A vs. G 75 (21.3%)/277 (78.7%) 31 (31.0%)/69 (69.0%) 0.603 0.367–0.988 0.043*
Dominant GG vs. AG+AA 108 (61.4%)/68 (38.6%) 25 (50.0%)/25 (50.0%) 1.588 0.844–2.988 0.150
Recessive AG+GG vs. AA 169 (96.0%)/7 (4.0%) 44 (88.0%)/6 (12.0%) 3.292 1.053–10.292 0.032*
Overdominant AA+GG vs. AG 115 (65.4%)/61 (34.6%) 31 (62.0%)/19 (38.0%) 1.155 0.603–2.213 0.663

CI, confidence interval; OR, odds ratio

*p<0.05