Table 3.
Genotypic and allelic distribution of the P2Y12R gene between patients with negative intracranial imaging and controls
| SNP | Genetic model | Genotype/allele | Cases | Controls | OR | 95% CI | p value |
|---|---|---|---|---|---|---|---|
| rs1491974 | Codominant | AA vs. AG vs. GG | 16 (16.3%)/49 (50.0%)/33 (33.7%) | 14 (28.0%)/26 (52.0%)/10 (20.0%) | - | - | 0.112 |
| Allele contrast | A vs. G | 81 (41.3%)/115 (58.7%) | 54 (54.0%)/46 (46.0%) | 0.600 | 0.369–0.975 | 0.038* | |
| Dominant | GG vs. AG+AA | 33 (33.7%)/65 (66.3%) | 10 (20.0%)/40 (80.0%) | 2.031 | 0.904–4.564 | 0.083 | |
| Recessive | AG+GG vs. AA | 82 (83.7%)/16 (16.3%) | 36 (72.0%)/14 (28.0%) | 1.993 | 0.880–4.513 | 0.095 | |
| Overdominant | AA+GG vs. AG | 49 (50.0%)/49 (50.0%) | 24 (48.0%)/26 (52.0%) | 1.083 | 0.548–2.142 | 0.818 | |
| rs6798347 | Codominant | AA vs. AG vs. GG | 3 (3.1%)/39 (39.8%)/56 (57.1%) | 6 (12.0%)/19 (38.0%)/25 (50.0%) | - | - | 0.096 |
| Allele contrast | A vs. G | 45 (23.0%)/151 (77.0%) | 31 (31.0%)/69 (69.0%) | 0.663 | 0.387–1.137 | 0.134 | |
| Dominant | GG vs. AG+AA | 56 (57.1%)/42 (42.9%) | 25 (50.0%)/25 (50.0%) | 1.333 | 0.673–2.641 | 0.409 | |
| Recessive | AG+GG vs. AA | 95 (96.9%)/3 (3.1%) | 44 (88.0%)/6 (12.0%) | 4.318 | 1.032–18.067 | 0.062 | |
| Overdominant | AA+GG vs. AG | 59 (60.2%)/39 (39.8%) | 31 (62.0%)/19 (38.0%) | 0.927 | 0.461–1.867 | 0.832 |
CI, confidence interval; OR, odds ratio
∗p<0.05