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. 2023 Feb 20;9(3):e13959. doi: 10.1016/j.heliyon.2023.e13959

Fig. 2.

Fig. 2

Schematic diagram depicting the impact of G-quadruplex ligands on cancerous cells. The majority of G-quadruplex ligands promote slower development. These growth alterations are the result of changes in biological mechanisms. Based on the ligands and cell types G-quadruplex stabilisation can result in alterations in (a) telomere maintenance (b) oncogenic gene expression (c) enhanced genomic instability.