Table 1.
Differences in baseline characteristics between men and women
| Demographic variable | Men (n = 444) | Women (n = 197) | P |
|---|---|---|---|
| Age, median (IQR), y | 65 (60–72.5) | 60 (55–66) | < 0.001 |
| Diabetes | 142 (32) | 55 (27.9) | 0.3 |
| Hypertension | 266 (59.9) | 108 (54.8) | 0.23 |
| Hyperlipidemia | 289 (65.1) | 140 (71.1) | 0.14 |
| CKD | 75 (16.9) | 14 (7.1) | 0.001 |
| COPD | 213 (48) | 75 (38.1) | 0.02 |
| CAD | 83 (18.7) | 22 (11.2) | 0.02 |
| PVD | 57 (12.8) | 7 (3.6) | < 0.001 |
| CHF | 47 (10.6) | 16 (8.1) | 0.33 |
| Atrial fibrillation | 41 (9.2) | 12 (6.1) | 0.18 |
| History of malignancy | 88 (19.8) | 16 (8.1) | < 0.001 |
| CVA | 96 (21.6) | 30 (15.2) | 0.06 |
| Bipolar disease | 27 (6.1) | 25 (12.7) | 0.005 |
| Smoking history | 270 (60.8) | 101 (51.3) | 0.02 |
| White race | 340 (81.3) | 151 (83.9) | 0.42 |
| Black race | 69 (15.5) | 22 (11.2) | 0.14 |
| Medications on admission | |||
| Beta-blocker | 148 (33.8) | 59 (30.3) | 0.38 |
| ACE-Is/ARB | 174 (39.7) | 76 (39) | 0.86 |
| Antiplatelets | 199 (45.4) | 74 (37.9) | 0.08 |
| Anticoagulation | 40 (9.1) | 16 (8.2) | 0.71 |
| Statin | 191 (43.6) | 83 (42.6) | 0.81 |
| Calcium channel blocker | 74 (16.9) | 28 (14.4) | 0.42 |
| Trigger factor | |||
| Emotional trigger | 33 (8.1) | 40 (22.6) | < 0.001 |
| Physical trigger | 281 (68.7) | 78 (44.1) | < 0.001 |
| No trigger factor identified | 95 (23.2) | 59 (33.3) | 0.01 |
| Location | |||
| Initial admission for TC | 280 (65.1) | 161 (83) | < 0.001 |
| Already admitted to inpatient general ward | 87 (20.2) | 20 (10.3) | < 0.001 |
| Already admitted to ICU | 57 (13.3) | 7 (3.6) | < 0.001 |
| Operating room | 6 (1.4) | 6 (3.1) | 0.15 |
Values are n (%), unless otherwise indicated.
ACE-I, angiotensin-converting enzyme inhibitor; ARB, angiotensin II receptor blocker; CAD, coronary artery disease; CHF, congestive heart failure; CKD, chronic kidney disease; COPD, chronic obstructive pulmonary disease; CVA, cerebrovascular accident; ICU, intensive care unit; IQR, interquartile range; PVD, peripheral vascular disease; TC, Takotsubo cardiomyopathy.