Figure 7.

Molecular effects of cyclic stretch on endothelial cells lining the walls of the patterned vessel

(A) Hierarchical clustering of differentially expressed genes as a heatmap, displaying the mean expression of 30 most up- (top section) and down (bottom section) regulated genes between static and stretch samples. Light green to dark blue refers to low to high relative expression levels of genes.

(B) Volcano plot of the DEGs, with the threshold at a log₂fold change (>0.5) (padj. < 0.05, N = 1, n = 3).