Table 3.
Overview of AEs in all patients who received furmonertinib 160 mg monotherapy or combination therapy as subsequent treatment
| Adverse events | Grade 1 | Grade 2 | Grade 3 | Grade 4 |
|---|---|---|---|---|
| n (%) | n (%) | n (%) | n (%) | |
| General Disorders | ||||
| Fatigue | 2 (7.1) | 1 (3.6) | ||
| Decreased appetite | 2 (7.1) | 1 (3.6) | ||
| Hematologic toxicity | ||||
| Leukopenia | 3 (10.7) | 1 (3.6) | 1 (3.6) | |
| Anemia | 5 (17.9) | 2 (7.1) | ||
| Decrased platelet count | 1 (3.6) | |||
| Gastrointestinal toxicity | ||||
| Mucositis oral | 1 (3.6) | |||
| Diarrhea | 1 (3.6) | |||
| Renal toxicity | ||||
| Increased serum creatinine | 2 (7.1) | |||
| Metabolism disorders | ||||
| Hypocalcemia | 1 (3.6) | |||
| Hepatobiliary toxicity | ||||
| Increased ALT/AST | 4 (14.3) | 1 (3.6) |
n number, AEs adverse events, ALT alanine aminotransferase, AST aspartate aminotransferase