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. 2023 Mar 3;17(1):9. doi: 10.1186/s13065-023-00918-1

Table 6.

Analytical results for miscellaneous compounds presented as average ± standard deviation for triplicate measurements

Analyte Units Limit of Quanification ZYN (dry) ZYN (moist) NRT (lozenge) NRT (gum) Snus (pouch) Moist snuff (loose) Moist snuff (pouch)
Acetaldehyde µg/g 1.0 * * * 4.7 ± 0.3 10.0 ± 0 5.7 ± 0.2 4.8 ± 0.2
Aflatoxin B1 ng/g 0.1/1.0a * * * * * * *
Aflatoxin B2 ng/g 0.1/1.0a * * * * * * *
Aflatoxin G1 ng/g 0.1/1.0a * * * * * * *
Aflatoxin G2 ng/g 0.1/1.0a * * * * * * *
Ammonia µg/g 1.0 62 ± 1 66 ± 1 * 4.5 ± 0 847 ± 45 2300 ± 0 3900 ± 100
Anabasine µg/g 20.0 * * * * 28.5 ± 0.3 54.6 ± 1.5 42.5 ± 0.1
Coumarin µg/g 0.05 * * * * * 0.86 ± 0.02 0.65 ± 0.02
Crotonaldehyde µg/g 0.050 * * * * * * *
Ethyl carbamate ng/g 30 * * * * * * *
Formaldehyde µg/g 1.0 10.3 ± 0.6 1.5 ± 0.1 * * 1.6 ± 0.1 4.3 ± 0.1 2.0 ± 0.1
Nicotine (total) mg/g 0.01 7.63 ± 0.21 12.00 ± 0 3.20 ± 0.10 1.30 ± 0.10 8.13 ± 0.38 9.97 ± 0.06 8.47 ± 0.12
Nicotine (unprotonated)b mg/g 0.01 4.87 ± 0.36 7.87 ± 0 2.57 ± 0.14 1.28 ± 0.10 7.11 ± 0.28 3.23 ± 0.02 3.65 ± 0.05
Nitrite µg/g 1.0 * * * * * * *
Nornicotine µg/g 50 * * * * 162 ± 2 220 ± 4 129 ± 0
Ochratoxin A ng/g 0.50 * * * * 0.86 ± 0.05 * 2.90 ± 0.26

a Aflatoxin quantification limits were 0.1 ng/g for the NRT lozenge and 1.0 ng/g for the other tested products

b Unprotonated nicotine was calculated based on pH for the different products (ZYN dry 8.3, ZYN moist 8.3, NRT (lozenge) 8.6, NRT (gum) 9.9, snus 8.9, moist snuff (loose) 7.7, moist snuff (pouch) 7.9)

* The measured analyte was below the quantification limit