Table 1.
Demographic and Clinical Characteristics of Implicit-Coded Sepsis in NDCMS and NMSS from 2017 to 2019
| 2017 | 2018 | 2019 | |
|---|---|---|---|
| Sepsis-related admission† | |||
| Number of hospitals | 3315 | 3403 | 3496 |
| Number of admissions | 2,715,999 | 3,444,660 | 4,521,966 |
| Number of patients | 2,452,915 | 3,052,599 | 3,949,765 |
| Characteristics | |||
| Age, years (SD) | 47 ± 32 | 50 ± 31 | 51 ± 30 |
| Female, n (%) | 991,021 (40.4) | 1,231,287 (40.6) | 1,601,354 (40.6) |
| Charlson comorbidity index | |||
| None | 711,393 (29.0) | 821,534 (27.1) | 981,801 (24.9) |
| 1 | 541,863 (22.2) | 661,597 (21.9) | 821,313 (20.9) |
| 2–4 | 891,741 (36.3) | 1,141,125 (37.6) | 1,541,997 (39.1) |
| > 4 | 301,918 (12.3) | 401,333 (13.4) | 591,654 (15.2) |
| Comorbidities, n (%) | |||
| Myocardial infarction | 71,013 (2.9) | 91,497 (3.0) | 121,208 (3.1) |
| Congestive heart failure | 571,766 (23.4) | 731,272 (24.0) | 961,826 (24.4) |
| Peripheral vascular disease | 121,240 (5.1) | 171,165 (5.8) | 261,608 (6.8) |
| Cerebrovascular disease | 421,972 (17.5) | 571,132 (18.7) | 801,033 (20.3) |
| Dementia | 21,624 (1.1) | 31,814 (1.2) | 51,799 (1.3) |
| Chronic pulmonary disease | 461,668 (18.9) | 611,075 (20.1) | 831,529 (21.3) |
| Rheumatic disease | 21,802 (1.2) | 31,650 (1.2) | 41,067 (1.2) |
| Peptic ulcer disease | 51,474 (2.4) | 71,071 (2.6) | 111,991 (2.8) |
| Mild liver disease | 411,055 (16.8) | 521,320 (17.1) | 721,643 (18.3) |
| Moderate or severe liver disease | 271,767 (11.3) | 381,856 (12.5) | 531,629 (13.5) |
| Diabetes without chronic complication | 311,793 (12.7) | 401,764 (13.2) | 551,549 (13.9) |
| Diabetes with chronic complication | 71,935 (3.1) | 101,431 (3.3) | 141,791 (3.6) |
| Hemiplegia or paraplegia | 1,159 (0.3) | 11,277 (0.4) | 21,005 (0.5) |
| Renal disease | 311,686 (12.9) | 361,735 (11.9) | 511,651 (13.1) |
| Malignancy | 221,250 (9.0) | 291,540 (9.7) | 411,802 (10.5) |
| Metastatic solid tumor | 61,773 (2.8) | 91,557 (3.2) | 141,979 (3.6) |
| AIDS/HIV | 11,777 (0.6) | 11,518 (0.6) | 21,766 (0.6) |
| Sepsis-related death‡ | |||
| Numbers of decedents | 262,935 | 271,095 | 272,698 |
| Age, years (SD) | 74 (18) | 75 (18) | 75 (18) |
| Female, n (%) | 109,613 (41.7) | 112,268 (41.4) | 112,294 (41.2) |
| Comorbidities, n (%) | |||
| Chronic pulmonary disease | 139,623 (53.1) | 139,622 (51.5) | 134,258 (49.2) |
| Malignancy | 21,735 (8.3) | 21,986 (8.1) | 22,505 (8.3) |
| Cerebrovascular disease | 17,017 (6.5) | 19,271 (7.1) | 21,506 (7.9) |
| Cardiovascular diseases | 6099 (2.3) | 6654 (2.5) | 6894 (2.5) |
| Diabetes | 2520 (1) | 2736 (1) | 3044 (1.1) |
| Renal disease | 593 (0.2) | 710 (0.3) | 673 (0.2) |
| Place of death, n (%) | |||
| Hospital | 70,881 (27.0) | 76,066 (28.1) | 81,905 (30.0) |
| Home | 183,389 (69.7) | 187,421 (69.1) | 182,791 (67.0) |
NDCMS National Data Center for Medical Service; NMSS National Mortality Surveillance System; COPD Chronic obstructive pulmonary disease; Malignancy Any malignancy, including lymphoma and leukemia, except malignant neoplasm of skin; HIV Human immunodeficiency virus; SD Standard deviation
†: Identified from NDCMS
‡: Identified from NMSS