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. 2023 Mar 4;27:84. doi: 10.1186/s13054-023-04385-x

Table 2.

Incidence, Case Fatality Rate and Mortality Rate of Implicit-coded Sepsis from 2017 to 2019

2017 2018 2019
Crude
Total
 Annual sepsis incidence, per 100,000 population 308.70 (305.95–311.45) 332.50 (329.72–335.28) 370.53 (367.61–373.45)
 In-hospital case fatality rate, % 6.83 (6.80–6.86) 6.78 (6.75–6.81) 6.53 (6.51–6.56)
 In-hospital mortality rate, per 100,000 population 21.08 (20.92–21.24) 22.56 (22.4–22.72) 24.21 (24.04–24.38)
Female
 Annual sepsis incidence, per 100,000 population 262.75 (258.89–266.61) 283.79 (279.85–287.73) 320.15 (315.97–324.33)
 In-hospital case fatality rate, % 6.07 (6.02–6.12) 5.95 (5.90–5.99) 5.68 (5.64–5.71)
 In-hospital mortality rate, per 100,000 population 15.96 (15.77–16.15) 16.87 (16.67–17.07) 18.17 (17.96–18.38)
Male
 Annual sepsis incidence, per 100,000 population 353.92 (349.96–357.88) 380.64 (376.65–384.63) 421.29 (417.13–425.45)
 In-hospital case fatality rate, % 7.35 (7.30–7.39) 7.36 (7.32–7.40) 7.12 (7.09–7.16)
 In-hospital mortality rate, per 100,000 population 26.00 (25.76–26.24) 28.02 (27.77–28.27) 30.01 (29.75–30.27)
Standardized
Total
 Annual sepsis incidence, per 100,000 population 342.06 (328.5–355.62) 359.26 (345.4–373.12) 429.71 (414.11–445.31)
 In-hospital case fatality rate, % 5.06 (5.00–5.13) 4.88 (4.83–4.94) 4.46 (4.42–4.50)
 In-hospital mortality rate, per 100,000 population 17.32 (16.67–17.97) 17.55 (16.90–18.20) 19.16 (18.49–19.83)
Female
 Annual sepsis incidence, per 100,000 population 269.12 (255.55–282.69) 275.72 (262.16–289,28) 343.37 (327.75–358.99)
 In-hospital case fatality rate, % 4.36 (4.26–4.45) 4.24 (4.16–4.32) 3.77 (3.71–3.84)
 In-hospital mortality rate, per 100,000 population 11.72 (11.19–12.25) 11.70 (11.17–12.23) 12.95 (12.41–13.49)
Male
 Annual sepsis incidence, per 100,000 population 418.54 (403.49–433.59) 445.89 (430.5–461.28) 519.06 (502.14–535.98)
 In-hospital case fatality rate, % 5.76 (5.67–5.85) 5.52 (5.45–5.59) 5.14 (5.08–5.20)
 In-hospital mortality rate, per 100,000 population 24.11 (23.32–24.90) 24.61 (23.83–25.39) 26.66 (25.85–27.47)

Data in parentheses are 95% confidence intervals. In-hospital sepsis case fatality rate = the proportion of patients with sepsis who die in hospitals among all hospitalized sepsis patients over one calendar year; In-hospital sepsis mortality rate = the proportion of all in-hospital sepsis-related deaths among the whole population over one calendar year

†: Refers to age standardized for sex