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Top five L1000 small molecules predicted to upregulate the expression of MEG3
| Rank | Drug | Up/down | Mean PCC | P-value |
|---|---|---|---|---|
| 1 | RN-1734 | Up | 0.03492403 | 4.90E−19 |
| 2 | Amprenavir | Up | 0.02721223 | 2.67E−16 |
| 3 | SA-441350 | Up | 0.03891477 | 1.22E−15 |
| 4 | GW-788388 | Up | 0.03600107 | 3.35E−15 |
| 5 | GALR3 | Up | 0.03087975 | 2.41E−14 |
L1000 small molecules are ranked by P-value between MEG3 and the genes in the up gene-set small-molecule signatures.
