Table 3.

Adverse Events Using SITT and SIDT

Adverse Events	SITT, n = 52	SIDT, n = 49	P-value
Any adverse events	15 (28.9)	12 (24.5)	0.7
Serious adverse events	0 (0)	0 (0)	1.0
Adverse events leading to discontinuation	0 (0)	0 (0)	1.0
Adverse events leading to death	0 (0)	0 (0)	1.0
Dysphonia	5 (9.6)	7 (14.3)	0.5
Transient coughing after administration	4 (7.7)	2 (4.1)	0.7
Dry mouth	5 (9.6)	0 (0)	0.1
Respiratory tract infections	2 (3.9)	1 (2.0)	1.0
Dyspepsia	2 (3.9)	0 (0)	0.5
Oral candidiasis	1 (1.9)	0 (0)	1.0
Diarrhea	0 (0)	1 (2.0)	0.5
Leg muscle cramps	0 (0)	1 (2.0)	0.5

Note: No patients had episodes of pneumonia.

Abbreviations: SIDT; single-inhaler dual therapy, SITT; single-inhaler triple therapy.