Table 4.
The diagnosis of patients with false negative mNGS
| Patient no. | Age (years) | Gender | Syndrome | Pathogen | Approaches to diagnosis |
|---|---|---|---|---|---|
| A | 39 | M | Meningitis | Bacteria | Discover the inner ear abscess |
| B | 48 | M | Meningoencephalitis | Bacteria | The clinical and CSF characteristics, effective antibiotic treatment |
| C | 56 | M | Encephalitis | Bacteria and/or virus | |
| D | 59 | M | Encephalitis | Bacteria | |
| E | 56 | M | Encephalitis | Tuberculosis | The second CSF mNGS and specialist consultation |
| F | 14 | M | Encephalitis with myelitis | Bacteria | Discover the inner ear abscess |
| G | 34 | M | Meningoencephalitis | Japanese B virus | Specific antibody test |
| H | 47 | M | Encephalitis | Tuberculosis | CSF-Xpert, specialist consultation, effective anti-TB treatment |
| I | 19 | M | Meningitis | FFI | Genetic screen and PCR (D178N mutation) |
FFI: fatal familiar insomnia.