FIGURE 2.

Relationship between ICCs and power with L = 2 co-primary endpoints. ICCs include the within-period endpoint-specific ICCs $\left({\rho }_0^1=0.1,{\rho }_0^2\right)$, between-period endpoint-specific ICC $\left({\rho }_1^1,{\rho }_1^2\right)$, within-period and between-period between-endpoint ICCs $\left({\rho }_0^{12},{\rho }_1^{12}\right)$, and intra-subject ICC $\left({\rho }_2^{12}\right)$. Various ${\rho }_2^{12}$ values are shown on the y-axis and various ${\rho }_0^{12}$ specifications are shown on the x-axis as a ratio of $\left({\rho }_0^1,{\rho }_0^2\right)$. Between-period ICCs are defined by CAC. Darker colors denote higher power.