Table 4.
HIV and immunologic related characteristics of the 80 PLWH with moderate and severe periodontitis
| Mean (SD) or median (IQR) | Participants with moderate periodontitis (n = 34) | Participants with severe periodontitis (n = 46) | P value | |
|---|---|---|---|---|
| CD4 + (cells/mm3) | 670.3 (273.7) | 706.7 (274) | 643.3 (273.1) | 0.309 |
| Naive CD4 + T cells (% of CD4 + T cells) | 26.8 (14.3) | 28.6 (15.1) | 25.5 (13.7) | 0.344 |
| CD4 + HLA-DR + T cells (% of CD4 + T cells)* | 14.3 (11–26) | 13.0 (10–21) | 15.0 (12–30) | 0.124# |
| CD4 + CD38 + T cells (% of CD4 + T cells) | 45.1 (15.2) | 47.3 (15.0) | 43.5 (15.2) | 0.266 |
| CD4 + HLA-DR + + CD38 + T cells (% of CD4 + T cells)* | 4.6 (4–8) | 4.7 (3–8) | 4.5 (4–8) | 0.685# |
| CD4 + CD28-CD57 + T cells (% of CD4 + T cells) | 6.6 (6.1) | 5.9 (4.2) | 7.1 (7.2) | 0.331 |
| CD3 + (cells/mm3) | 1428.5 (1165–1785) | 1403.0 (1154–1732) | 1461.0 (1147–1796) | 0.640# |
| CD8 + (cells/mm3) | 695.5 (523–884) | 681.0 (456–808) | 701.0 (559–957) | 0.411# |
| Naive CD8 + T cells (% of CD8 + T cells) | 10.3 (5–19) | 9.8 (5–18) | 10.1 (5–20) | 0.992# |
| CD8 + HLA-DR + T cells (% of CD8 + T cells)* | 22.9 (18–36) | 22.8 (17–33) | 22.9 (18–40) | 0.751# |
| CD8 + CD38 + T cells (% of CD8 + T cells) | 29.6 (19–38) | 28.3 (20–40) | 30 (18–35) | 0.400# |
| CD8 + HLA-DR + + CD38 + T cells (% of CD8 + T cells)* | 8.1 (5–13) | 8.6 (6–13) | 7.7 (5–12) | 0.392 |
| CD8 + CD28-CD57 + T cells (% of CD8 + T cells) | 11.4 (7–23) | 8.9 (6–19) | 16.5 (9–26) | 0.035# |
| CRP (mg /l) | 1.2 (0.6–2.3) | 0.8 (0.5–2.0) | 1.6 (0.9–3.0) | 0.020# |
| IL-6 (pg/ml) | 0.7 (0.0–1.8) | 0.6 (0.0–1.5) | 0.9 (0.0–2.6) | 0.211# |
| sCD14 (µg/ml) | 3.9 (1.3) | 3.6 (1.3) | 4.1 (1.3) | 0.079 |
| sPD-1 (pg/ml) | 204.8 (163–183) | 208.4 (176–260) | 184 (162–250) | 0.243# |
| CXCL10* (pg/ml) | 147 (118–183) | 136.4 (116–173) | 155.1 (118–190) | 0.507# |
| sCD163 (ng/ml) | 34.0 (28–50) | 39.5 (26–57) | 33.8 (29–45) | 0.853# |
| LPS/DPLG70 (ng/ml) | 136 (46.3) | 139.0 (50.3) | 133.7 (43.5) | 0.623 |
*data was not known for 1 person
#Mann–Whitney U test applied due to skewed data distribution