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. 2022 Dec 20;7(1):100020. doi: 10.1016/j.rpth.2022.100020

Figure 1.

Figure 1

Flow chart of study selection. The first literature search was conducted on February 15, 2021. After study selection, 27 studies were eligible for inclusion. The search was updated on December 29, 2021. Four studies were eligible for inclusion; however, these cohorts overlapped with previously included studies. Therefore, we had to exclude 4 studies. In total, 27 studies were included in this systematic review and meta-analysis.