Pooled odds ratio (OR)s of determinants for complete success in primary ITI (immune tolerance induction). All presented pooled ORs show the chance for complete ITI success. Every determinant is categorized in 2 groups and the reference group is reported. For example, the pooled OR, for peak titer during ITI <100 BU/mL shows a 2.66 increased chance for complete ITI success compared to ≥100 BU/mL. On the other hand, the pooled OR, for age at inhibitor development ≤12 months shows a 0.72 decreased chance for complete ITI success, thus favoring persons older than 12 months.