Table 2.
Baseline characteristics of the study population
| Costa-Pinto (MAVERICK) | El Adly | Ali | Santer (MIDAS) | |
|---|---|---|---|---|
| Age in years | ||||
| Midodrine | 61.5 [53, 72]b | 61.8 ± 15.1a | – | 70 ± 12.6a |
| Control | 64 [51, 76.75]b | 59.8 ± 15.1a | – | 66.7 ± 14.7a |
| Male % | ||||
| Midodrine | 68.8 | 50 | – | 54.5 |
| Control | 60 | 43.3 | – | 48.5 |
| Weight (kg) | ||||
| Midodrine | 71 [65, 80]b | 82.9 ± 14.5a | – | 78.6 ± 22.4a |
| Control | 80 [71, 88.75]b | 84.4 ± 15.1a | – | 82.3 ± 23.5a |
| APACHE score | ||||
| Midodrine | 49.5 [41, 56.25]b (APACHE III) | 24 [13–39]b (APACHE II) | – | 14.7 ± 5.2a (APACHE II) |
| Control | 48.5 [38.25, 58]b (APACHE III) | 21.5 [7–39]b (APACHE II) | – | 14.8 ± 5.9a (APACHE II) |
| Diabetes % | ||||
| Midodrine | 6.2 | 53.3 | – | – |
| Control | 0 | 30 | – | – |
| Hypertension % | ||||
| Midodrine | 37.5 | 63.3 | – | – |
| Control | 33.3 | 56.7 | – | – |
| HR (beats per minute) | ||||
| Midodrine | 76 [70, 85]b | 110 [72–130]b | 120.53 ± 11.91a | – |
| Control | 77.5 [65.5, 85]b | 115 [79–148]b | – | – |
| MAP (mmHg) | ||||
| Midodrine | 72 [70, 80]b | 60 [50–75]b | 65.83 ± 20.29a | 75.9 ± 9.4 a |
| Control | 75 [70, 75.75]b | 70 [47–73]b | 62.87 ± 19.21a | 72.8 ± 8.2a |
IQR interquartile range, SD standard deviation, HR heart rate, MAP mean arterial blood pressure, APACHE score Acute Physiology and Chronic Health Evaluation Score
aMean (SD)
bMedian (IQR)