TABLE 1.

Surface expression of lineage and activation markers on lymphoid cells^a

Cells	Marker	+/+ Mice		−/− Mice
		Expression (mean % of cells)	SD	Expression (mean % of cells)	SD
Lymph node	CD4	55.67	5.11	44.84	6.67
	CD8	33.40	1.72	42.81	6.38
	TCRαβ	86.14	7.92	82.75	1.22
	CD11	0.76	0.13	2.35	0.50
	CD25	8.34	5.41	17.02	5.74
	CD28	1.17	0.44	3.23	1.70
	CD45	98.25	0.53	97.71	2.04
Spleen	B220	16.52	2.79	12.95	3.37
	IgM	11.72	1.25	10.11	0.02
	IgD	16.04	1.50	11.81	2.05
	CD4	43.43	6.15	43.97	1.24
	CD8	9.39	0.48	17.19	8.39
Thymus	CD4	85.03	2.49	86.025	3.44
	CD8	57.91	4.65	71.38	0.32
	CD4 + CD8	51.67	6.25	64.35	3.78
	TCRαβ	37.82	6.38	23.92	1.5
	CD3	12.93	3.07	11.35	3.55
	CD5	24.21	8.08	25.63	2.07
PMA-stimulated spleen	CD69
	0 h	1.63	0.21	2.55	1.41
	12 h	75.72	5.27	77.09	10.22

^aUnstimulated spleen, thymus, and lymph node cells from two pairs of HePTP^−/− and HePTP^+/+ mice were stained with the indicated monoclonal antibodies conjugated directly to PE, FITC, or biotin. Surface expression was analyzed by flow cytometry.