TABLE 2.
Associations between recipient, donor and procedure characteristics and DGF in final multivariable analyses (n = 687).
| Recipient/Donor/Procedure characteristics | Univariable odds ratio (95% CI a ) | p-value | Multivariable odds ratio (95% CI a ) | p-value |
|---|---|---|---|---|
| Pre-transplant elevated anti-LG3 antibodies b | ||||
| In cold static storage | 1.58 (1.03, 2.39) | 0.04 | 1.75 (1.02, 3.00) | 0.04 |
| Placed on a hypothermic perfusion machine | 0.65 (0.33, 1.29) | 0.22 | 0.78 (0.44, 1.37) | 0.38 |
| Recipient age at transplant (per 10 years higher) | 1.17 (1.04, 1.31) | <0.01 | 0.98 (0.97, 1.00) | 0.06 |
| Recipient African American race (versus Caucasian) | 1.80 (1.03, 3.14) | 0.04 | 0.84 (0.39, 1.79) | 0.65 |
| Time on dialysis pre-transplant (per 1-month higher) | 1.00 (1.00, 1.20) | <0.01 | 1.01 (1.01, 1.02) | <0.01 |
| Recipient diabetes | 2.34 (1.63, 3.36) | <0.01 | 2.14 (1.35, 3.39) | <0.01 |
| Recipient positive CMV serology | 1.28 (0.94, 1.74) | 0.11 | 1.02 (0.68, 1.54) | 0.92 |
| Recipient ACE inhibitor/angiotensin-2 blocker use at transplantation | 0.57 (0.42, 0.79) | <0.01 | 0.54 (0.37, 0.81) | <0.01 |
| Previous transplantations | 1.69 (1.04, 2.74) | 0.03 | 1.61 (0.84, 3.10) | 0.15 |
| Thymoglobulin induction | 2.34 (1.63, 3.35) | <0.01 | 2.24 (1.36, 3.69) | <0.01 |
| Donor type (References neurologically deceased) | ||||
| Living donor | 0.12 (0.06, 0.21) | <0.01 | 0.21 (0.11, 0.41) | <0.01 |
| Donor after cardiac arrest | 4.10 (2.37, 7.11) | <0.01 | 4.99 (2.62, 9.50) | <0.01 |
| Donor age (per 10-year higher) | 1.30 (1.17, 1.45) | <0.01 | 1.48 (1.28, 1.72) | <0.01 |
| Donor height (per 10 cm higher) | 0.82 (0.71, 0.95) | <0.01 | 0.75 (2.34, 15.63) | <0.01 |
| Donor peripheral vascular disease | 2.00 (1.18, 3.40) | 0.01 | 0.96 (0.50, 1.87) | 0.91 |
| Donor diabetes | 1.52 (0.86, 2.69) | 0.15 | 0.94 (0.48, 1.85) | 0.59 |
| Donor terminal serum creatinine ≥120 umol/L | 4.69 (2.05, 10.69) | <0.01 | 6.14 (2.37, 15.92) | <0.01 |
| Center 1 | 0.31 (0.22, 0.42) | <0.01 | 0.38 (0.23, 0.63) | <0.01 |
| Transplant date (per 1 year higher) | 1.04 (0.97, 1.11) | 0.26 | 1.03 (0.93, 1.13) | 0.86 |
CI, confidence interval.
The p-value for the interaction between anti-LG3 and use of hypothermic pump is 0.02.