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. 2023 Feb 20;36:10749. doi: 10.3389/ti.2023.10749

TABLE 2.

Associations between recipient, donor and procedure characteristics and DGF in final multivariable analyses (n = 687).

Recipient/Donor/Procedure characteristics Univariable odds ratio (95% CI a ) p-value Multivariable odds ratio (95% CI a ) p-value
Pre-transplant elevated anti-LG3 antibodies b
 In cold static storage 1.58 (1.03, 2.39) 0.04 1.75 (1.02, 3.00) 0.04
 Placed on a hypothermic perfusion machine 0.65 (0.33, 1.29) 0.22 0.78 (0.44, 1.37) 0.38
Recipient age at transplant (per 10 years higher) 1.17 (1.04, 1.31) <0.01 0.98 (0.97, 1.00) 0.06
Recipient African American race (versus Caucasian) 1.80 (1.03, 3.14) 0.04 0.84 (0.39, 1.79) 0.65
Time on dialysis pre-transplant (per 1-month higher) 1.00 (1.00, 1.20) <0.01 1.01 (1.01, 1.02) <0.01
Recipient diabetes 2.34 (1.63, 3.36) <0.01 2.14 (1.35, 3.39) <0.01
Recipient positive CMV serology 1.28 (0.94, 1.74) 0.11 1.02 (0.68, 1.54) 0.92
Recipient ACE inhibitor/angiotensin-2 blocker use at transplantation 0.57 (0.42, 0.79) <0.01 0.54 (0.37, 0.81) <0.01
Previous transplantations 1.69 (1.04, 2.74) 0.03 1.61 (0.84, 3.10) 0.15
Thymoglobulin induction 2.34 (1.63, 3.35) <0.01 2.24 (1.36, 3.69) <0.01
Donor type (References neurologically deceased)
 Living donor 0.12 (0.06, 0.21) <0.01 0.21 (0.11, 0.41) <0.01
 Donor after cardiac arrest 4.10 (2.37, 7.11) <0.01 4.99 (2.62, 9.50) <0.01
Donor age (per 10-year higher) 1.30 (1.17, 1.45) <0.01 1.48 (1.28, 1.72) <0.01
Donor height (per 10 cm higher) 0.82 (0.71, 0.95) <0.01 0.75 (2.34, 15.63) <0.01
Donor peripheral vascular disease 2.00 (1.18, 3.40) 0.01 0.96 (0.50, 1.87) 0.91
Donor diabetes 1.52 (0.86, 2.69) 0.15 0.94 (0.48, 1.85) 0.59
Donor terminal serum creatinine ≥120 umol/L 4.69 (2.05, 10.69) <0.01 6.14 (2.37, 15.92) <0.01
Center 1 0.31 (0.22, 0.42) <0.01 0.38 (0.23, 0.63) <0.01
Transplant date (per 1 year higher) 1.04 (0.97, 1.11) 0.26 1.03 (0.93, 1.13) 0.86
a

CI, confidence interval.

b

The p-value for the interaction between anti-LG3 and use of hypothermic pump is 0.02.