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. 2023 Feb 20;15:1087318. doi: 10.3389/fnagi.2023.1087318

Table 2.

Sociodemographic and medical characteristics.

Variable Frailty Frailty with sarcopenia t/z/χ2 Value of p
N = 51 N = 44
Age (years) 85.176 ± 7.320 87.522 ± 6.296 −1.661 0.100
BMI (kg/m2) 24.294 ± 3.313 21.959 ± 3.079 3.539 0.001
SMI (kg/m2) 7.200 ± 1.011 5.780 ± 5.555 7.714 <0.001
Cr (μmol/L) 76.467 ± 27.512 77.066 ± 15.734 −0.128 0.899
UA (μmol/L) 346.455 ± 107.029 325.614 ± 98.982 0.978 0.329
Alb (g/L) 40.931 ± 5.904 42.602 ± 7.825 −1.183 0.240
TC (mmol/L) 3.94 ± 0.955 3.827 ± 1.264 0.496 0.621
TG (mmol/L) 1.490 ± 0.735 1.333 ± 0.697 1.056 0.294
HDLC (mmol/L) 1.230 ± 0.339 1.202 ± 0.327 0.396 0.693
LDLC (mmol/L) 2.462 ± 0.613 2.266 ± 0.675 1.484 0.141
HBDH (U/L) 150.582 ± 35.454 150.932 ± 41.879 −0.044 0.965
Gait speed (cm/s) 51.333 ± 17.765 39.863 ± 11.027 3.558 0.001
MoCA 18.157 ± 4.483 17.295 ± 6.021 0.797 0.427
M visuospatial/executive function 2.156 ± 1.433 2.205 ± 1.636 −0.151 0.880
M naming 2.803 ± 0.633 2.659 ± 0.568 1.165 0.246
M attention 4.471 ± 1.447 4,136 ± 1.607 1.066 0.289
M language 1.667 ± 0.887 1.523 ± 1.067 0.718 0.475
M abstraction 1.216 ± 0.672 1.295 ± 0.733 −0.553 0.582
M delayed memory 0.882 ± 1.227 1.182 ± 1.419 −1.103 0.273
M orientation 4.980 ± 1.225 4.227 ± 1.626 2.569 0.012
Clock drawing task 2.118 ± 1.321 2.045 ± 1.396 0.259 0.797
FREID scores 4 (3,4) 5 (5,5) −8.377 <0.001
4.57 m walking time(s) 9.327 (7.371,11.718) 12.189 (9.235,14.281) −2.905 0.004
Grip strength(kg) 15.5 (11.3,22.7) 14.9 (9.95,21.7) −0.795 0.472
Gender
Female, n (%) 29 (56.86) 16 (36.36) 3.981 0.046
Male, n (%) 22 (43.14) 28 (63.64)
Osteoporotic, n (%)
No 45 (88.24) 30 (68.18) 5.715 0.017
Yes 6 (11.76) 14 (31.82)
Hypertension, n (%)
No 18 (35.29) 17 (38.64) 0.113 0.736
Yes 33 (64.71) 27 (61.36)
Diabetes mellitus, n (%)
No 35 (68.63) 35 (79.55) 1.452 0.228
Yes 16 (31.37) 9 (20.45)
Cerebrovascular disease, n (%)
No 31 (60.78) 31 (70.45) 0.974 0.324
Yes 20 (39.22) 13 (29.55)
Coronary heart disease, n (%)
No 40 (78.43) 35 (79.55) 0.018 0.894
Yes 11 (21.57) 9 (20.45)
Anxiety/Depression, n (%)
No 42 (82.35) 37 (84.09) 0.051 0.821
Yes 9 (17.65) 7 (15.91)

BMI, Body mass index; SMI, skeletal muscle mass index; Cr, creatinine; UA, uric acid; Alb, albumin; TC, total cholesterol; TG, triglyceride; HDLC, high-density lipoprotein cholesterol; LDLC, low-density lipoprotein cholesterol; HBDH, hydroxybutyrate dehydrogenase.