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The effects of lesional MSCs in AD and psoriasis patients. Compared with MSCs from healthy donor, MSCs in skin lesion of AD and psoriasis patients can enhance the activation of Th1 and Th17 cells and promote the production of their pro-inflammatory cytokines including IL-4, IL-6, IL-13, IL-17A, IL-17F, IL-17C, CCL, TNF-α, and IFN-γ and suppress the activation of Treg.
