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. 2023 Feb 20;14:1079960. doi: 10.3389/fimmu.2023.1079960

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Copyright © 2023 Zheng, Ma, Yang, Liao, Cheng, Xue, Li, Fang, Lin, Zhang, Huang, Hu, Ma and Sun

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Heatmaps of peptide-specific responses in vaccinated with hypo- and hyperimmune responses. (A) Vaccinated were divided into two groups: hypoimmune and hyperimmune (green) responses. Regarding Group 1, light to dark (purple) coloration represents the timepoints before immunization, 30 days after the first dose, 30 days after the second dose, and 30 days after the third dose. (B) Peptide reactions collected by V3 + 30 (30 days after the third dose).