Figure 9.

Alteration of histopathological struture and mechanical property in human vaginal wall tissues of Old POP. (A) HE staining showing degenerative changes in vaginal tissue of old patient with POP. In patients with pelvic organ prolapse, the collagen fibers in the vaginal tissues became sparse and lax, losing their tight junctions and showing degenerative changes. (B) Stress-strain diagram of the anterior vaginal wall in patients with anterior vaginal wall prolapse. (C) Creep performance of the anterior vaginal wall in patients with anterior vaginal wall prolapse. (D) Relaxation performance of the anterior vaginal wall in patients with anterior vaginal wall prolapse. (E) Physical picture of universal mechanical tester.