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. 2023 Feb 20;14:1010858. doi: 10.3389/fphys.2023.1010858

TABLE 3.

Associations between initial (T0-T1) % changes in hormone levels and subsequent (T1-T2) % changes in anthropometrics.

Model 1 unadjusteda) Model 2 adjusted for age and sexb)
N β (95% CI ) Standardized β p β (95% CI ) Standardized β p
Dependent variable: T1-T2 ∆ % BMI
  T0-T1 ∆ % Leptin 39 0.004 (−0.075; 0.083) .017 .917 0.011 (−0.068; 0.090) .046 .782
  T0-T1 ∆ % Insulin 39 −0.062 (-0.123; -0.001) −.319 .048* −0.053 (−0.116; 0.011) −.271 .102
  T0-T1 ∆ % HMW Adiponectin 39 0.097 (−0.008; 0.203) .293 .070 0.110 (0.000; 0.220) .332 .050
  T0-T1 ∆ % GIP 38 −0.006 (−0.032; 0.021) −.070 .675 0.000 (−0.028; 0.029) .006 .974
  T0-T1 ∆ % PP 38 −0.032 (−0.090; 0.026) −.183 .272 −0.034 (−0.092; 0.023) −.195 .237
  T0-T1 ∆ % PYY 38 −0.035 (-0.069; -0.002) −.337 .039* −0.032 (−0.068; 0.003) −.308 .074
  T0-T1 ∆ % CCK 39 0.035 (−0.037; 0.106) .159 .333 0.014 (−0.064; 0.092) .064 .720
  T0-T1 ∆ % FGF21 38 −0.021 (-0.040; -0.003) −.360 .027* −0.021 (-0.040; -0.001) −.350 .038*
  T0-T1 ∆ % AgRP 38 0.040 (−0.025; 0.105) .203 .221 0.023 (−0.050; 0.096) .115 .533
Dependent variable: T1-T2 ∆ % WC
  T0-T1 ∆ % Leptin 39 −0.055 (−0.144; 0.033) −.205 .212 −0.047 (−0.135; 0.042) −.173 .290
  T0-T1 ∆ % Insulin 39 −0.046 (−0.118; 0.027) −.206 .209 −0.033 (−0.107; 0.042) −.148 .379
  T0-T1 ∆ % HMW Adiponectin 39 0.079 (−0.044; 0.202) .209 .201 0.103 (−0.024; −0.231) .274 .108
  T0-T1 ∆ % GIP 38 −0.018 (−0.047; 0.011) −.207 .213 −0.015 (−0.045; 0.015) −.169 .329
  T0-T1 ∆ % PP 38 −0.024 (−0.088; 0.040) −.126 .449 −0.027 (−0.091; 0.036) −.142 .391
  T0-T1 ∆ % PYY 38 −0.027 (−0.066; 0.013) −.224 .177 −0.019 (−0.061; 0.023) −.161 .359
  T0-T1 ∆ % CCK 39 −0.009 (−0.091; 0.074) −.035 .833 −0.041 (−0.129; 0.047) −.164 .353
  T0-T1 ∆ % FGF21 38 −0.015 (−0.037; 0.007) −.220 .184 −0.012 (−0.035; 0.011) −.175 .309
  T0-T1 ∆ % AgRP 38 0.026 (−0.049; 0.101) .118 .481 0.001 (−0.082; 0.085) .006 .973

CI = confidence interval; BMI = body-mass-index, WC = waist circumference; HMW, adiponectin = high-molecular-weight adiponectin, GIP = gastric inhibitory polypeptide; PP = pancreatic polypeptide; PYY = peptide tyrosine-tyrosine; CCK = cholecystokinin, FGF21 = fibroblast growth factor 21, AgRP = agouti-related protein. a) Univariable linear regressions were used with T0-T1% changes in hormone levels as predictor and T0-T2% changes in BMI/WC, as outcomes. b) Adjustment was performed using multiple linear regression.* indicates p < .05 (highlighted in bold text). None of the association was significant at the Bonferroni-corrected significance level α = 0.005.95% CI = 95% Confidence interval.