Table 1.
PHENSIM transcriptomic predicted values from Blanco-Melo et al. 2020.
| Overall Accuracy | Nodes Predicted as perturbed |
Nodes predicted as non-perturbed |
||||
|---|---|---|---|---|---|---|
| PPV | Sensitivity | Specificity | PPV | FNR | ||
| A549-ACE2 MOI 0.2 | 51.66% | 93.50% | 96.72% | 97.67% | 58.90% | 41.10% |
| A549-ACE2 MOI 2 | 71.72% | 96.88% | 99.24% | 99.13% | 60.04% | 39.96% |
| A549 MOI 0.2 | 83.74% | 68.75% | 100.00% | 99.86% | 85.64% | 14.36% |
| A549 MOI 2 | 78.20% | 97.41% | 97.20% | 99.58% | 77.47% | 22.53% |
| Calu-3 | 77.17% | 96.93% | 99.34% | 99.30% | 76.55% | 23.45% |
| NHBE | 82.43% | 67.65% | 95.83% | 99.69% | 86.48% | 13.52% |
PPV; Positive predictive value, FNR; False negative rate, NHBE; Normal Human Bronchial Epithelial cells. Blanco-Melo et al., Cell 2020 [14].