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. 2023 Mar 6;9(3):e14115. doi: 10.1016/j.heliyon.2023.e14115

Table 2.

PHENSIM proteomic predicted values from Bojkova et al. 2020.

Time (hours) All Proteins Proteins in Meta-pathway Predicted
Percentage
Accuracy PPV Sensitivity Specificity
2 5809 1914 6.95% 93.98% 95.45% 92.65% 95.38%
6 5809 1914 11.70% 93.75% 94.35% 97.66% 81.13%
10 5809 1914 10.45% 94.50% 95.27% 98.17% 77.78%
24 5809 1914 34.95% 97.91% 98.39% 97.87% 97.96%

All Proteins; number (N) of proteins quantified for each timepoint.

Proteins in Meta-pathway; number (N) of proteins present in KEGG, and therefore in the meta-pathway. Predicted Percentage; Percent (%) proteins for which PHENSIM could produce a prediction.

Accuracy, PPV, Sensitivity, and Specificity; the metrics used to compare our model with the actual proteomics data. PPV; Positive predictive value. Bojkova et al., Nature 2020 [9].