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. 2023 Feb 20;14:1113015. doi: 10.3389/fimmu.2023.1113015

Table 2.

Characteristics of the autoantibody positive patients.

Patient ID Age at onset (years) Sex CRP (mg/l) RF
(U/ml)
Anti-CCP(U/ml) DAS index Treatment Detected autoantibody
223 57 male 16 71 749 6.9 Methotrexat, Metilprednizolon, Sulfasalazine anti-FB IgG
240 52 female 128.47 2.27 anti-C1q IgG
243 75 male 360.9 2403.87 0.84 Tocilizumab anti-FB IgG
268 67 female 6.59 anti-C1q IgG
274 32 female 40 373 6.54 Methotrexat anti-FB IgG
277 52 female 120 452.76 5.25 Leflunomide anti-MBL IgG
282 80 male 497.89 3.09 Certolizumab pegol anti-FB IgG
288 73 female 249 399 0.91 Tocilizumab anti-FB IgA
348 73 female 617.34 anti-MBL IgG
547 41 female 3.0 Certolizumab pegol anti-FB IgG, IgA
557 64 female 290 5.4 anti-C1q IgG
587 45 male     61     anti-C1q IgG

Reference ranges:

RF (rheumatoid factor): >20 U/ml positive.

Anti-CCP (cyclic citrullinated peptide): <20 non-RA, >20 RA.

DAS index (disease activity score): <2.6 remission, 2.6-3.1 low disease activity, 3.1-5.1 moderate disease activity, >5.1 high disease activity.