Table 2.
Baseline characteristics based on the 50th percentile cut-off for the total number of micronuclei per 1000 BN cells in male participants.
| Parameter |
All |
LMF |
HMF |
p-value |
|---|---|---|---|---|
| Subjects | n = 64 |
n = 32 |
n = 32 |
|
| Mean ± SD | Mean ± SD | Mean ± SD | ||
| CBMN parameter | ||||
| Cells with MNi [per 1000 BN cells] | 9.2 ± 3.9 | 6.48 ± 1.49 | 11.88 ± 3.72 | <0.001 |
| Total number of MNi [per 1000 BN cells] | 10.3 ± 4.6 | 7.15 ± 1.45 | 13.42 ± 4.49 | <0.001 |
| Nuclear buds | 2.6 ± 1.71 | 2.27 ± 1.71 | 2.94 ± 1.67 | 0.077 |
| Nucleoplasmic bridges | 1.1 ± 1.02 | 0.98 ± 1.02 | 1.13 ± 1.05 | 0.279 |
| Apoptotic cells | 6.88 ± 5.94 | 6.92 ± 7.46 | 6.83 ± 4.02 | 0.862 |
| Necrotic cells | 4.00 ± 2.97 | 3.56 ± 2.46 | 4.44 ± 3.38 | 0.916 |
| Nuclear division index | 1.75 ± 0.25 | 1.74 ± 0.21 | 1.76 ± 0.29 | 0.931 |
| Body composition | ||||
| BMI [kg/m2] | 27.1 ± 4.5 | 25.8 ± 3.4 | 28.4 ± 5.1 | 0.025 |
| Waist to Hip Ratio | 0.98 ± 0.14 | 0.98 ± 0.17 | 0.98 ± 0.06 | 0.113 |
| Lean body mass [kg] | 68.4 ± 9.4 | 67.0 ± 9.0 | 70.0 ± 9.4 | 0.183 |
| Body cell mass[kg] | 33.2 ± 4.8 | 32.7 ± 4.6 | 33.6 ± 5.0 | 0.592 |
| Body fat [kg] | 17.1 ± 7.5 | 15.02 ± 5.8 | 19.0 ± 8.4 | 0.068 |
| Body fat [%] | 19.4 ± 5.6 | 17.9 ± 5.3 | 20.6 ± 5.8 | 0.054 |
| Functional parameters | ||||
| Arm curl dominant arm 30s [repetitions] | 19.0 ± 4.0 | 20.2 ± 4.5 | 17.8 ± 3.2 | 0.056 |
| Timed up and go [s] | 4.65 ± 0.78 | 4.47 ± 0.59 | 4.84 ± 0.95 | 0.129 |
| 6-min-walk test [m] | 650 ± 93 | 680 ± 90 | 618 ± 90 | 0.043 |
| 30s-chair stand test [repetitions] | 12.6 ± 2.3 | 13.4 ± 1.9 | 11.9 ± 2.5 | 0.017 |
| Handgrip dominant hand [kg] | 42.4 ± 7.3 | 42.8 ± 8.5 | 41.3 ± 5.8 | 0.726 |
| Blood parameters | ||||
| Vitamin D serum level (ng/mL) | 22.8 ± 5.5 | 22.54 ± 5.6 | 22.24 ± 6.24 | 0.220 |
| Erythrocytes [T/L] | 15.5 ± 1.2 | 15.5 ± 1.1 | 15.4 ± 1.4 | 0.980 |
| Hemoglobin [g/dl] | 44.4 ± 3.4 | 44.6 ± 3.2 | 44.3 ± 3.8 | 0.541 |
| Hematocrit [%] | 2.43 ± 4.41 | 1.71 ± 2.05 | 3.24 ± 5.99 | 0.548 |
| hs-CRP [mg/L] | 6.00 ± 3.47 | 6.00 ± 4.24 | 6.08 ± 2.73 | 0.011 |
| FRAP [μmol/L] | 1132 ± 191 | 1162 ± 186 | 1112 ± 204 | 0.277 |
| GSH [μmol/L] | 16.59 ± 3.27 | 16.55 ± 3.28 | 16.44 ± 3.34 | 0.727 |
| GSSG [μmol/L] | 8.83 ± 1.62 | 8.75 ± 1.32 | 8.78 ± 1.93 | 0.925 |
| GSH:GSSG ratio | 1.92 ± 0.42 | 1.92 ± 0.42 | 1.93 ± 0.43 | 0.851 |
| MDA [μmol/L] | 2.26 ± 0.49 | 2.21 ± 0.48 | 2.30 ± 0.52 | 0.347 |
| hs-Troponin [ng/L] | 4.95 ± 0.38 | 4.95 ± 0.37 | 4.96 ± 0.39 | 0.432 |
Data are presented as mean ± standard deviation. P-values (p < 0.05) were calculated using the Mann-Whitney U test, HMF group refers to the participants with greater MNi frequency than the Median of total MNi, and LMF refers to the group with less MNi frequency than the Median of total MNi.